7 Ways to Ensure Ethical and Safe Use of AI in Healthcare

May 13, 2025
Monica Ayre

Artificial intelligence (AI) is one of the hottest topics today, and for good reason. Its capabilities seem limitless, bringing to fruition what we once envisioned as mere dreams.

AI isn’t merely a buzzword in healthcare; it’s a powerful catalyst for change. AI has revolutionized healthcare in ways we couldn't have imagined a decade ago, from enhancing diagnostic accuracy to optimizing treatment plans and streamlining workforce efficiency through automation.

But with great power comes great responsibility. In healthcare, we’re not just working with algorithms and data; we’re dealing with people’s lives, sensitive medical information, and decisions that directly affect individual health and well-being. Missteps in AI use can have serious consequences.

As health professionals, we must use AI responsibly, with the assurance that it will ethically and safely serve the patients. How can we do that? Let's explore ways to use AI ethically and safely in healthcare.

7 Ways to Ensure Ethical and Safe Use of AI

AI integration in healthcare facilitated unprecedented progress, fundamentally changing how care was provided and managed. An AMA survey highlights that 65% of physicians agree AI has the potential to transform healthcare delivery positively.

However, as with any emerging technology, AI has challenges, especially on ethical and safety grounds. As we embrace this transformative path, we must practice caution. Responsible use of AI is underpinned by careful planning, adherence to ethics, and a commitment to patient safety. Here are seven strategies to leverage the power of AI ethically and safely.

Adhere to Ethical Principles

Ethical principles must be the foundation of artificial intelligence (AI) in healthcare. Healthcare providers relying on AI technology must ensure the following:

1. Transparency

AI tools rely heavily on data, and their effectiveness is directly linked to the data quality they are trained on. Healthcare providers can trust and rely on AI-generated outcomes only when they are fully aware of the quality of the data and its sources. This knowledge enables them to make informed decisions and provide clear explanations to patients regarding the AI's role in their care. Additionally, providers must inform patients about AI’s intervention in their care. It's pivotal to foster trust, understand the process, and raise concerns.

2. Bias

A key concern with AI in healthcare is the potential for racial, gender, linguistic, and socioeconomic biases. These biases often arise from the data used to train AI systems. If the datasets lack diversity or are skewed toward specific populations, AI can generate outcomes that are unfair or disadvantageous to others. To mitigate this, AI should be trained on diverse and specific datasets to ensure equity and reduce the risk of biased decision-making.

Healthcare providers can collaborate with AI developers during the training phase to incorporate diverse perspectives and ensure that the AI system is unbiased and effective in meeting the needs of all patient populations. Tailoring AI tools to align with practice needs enhances efficiency and improves outcomes.

3. Informed Consent

Providers must inform patients of AI's role in their care, including its potential benefits, risks, and limitations. They should also be notified of how their data is utilized in AI applications. Moreover, patients must retain the right to opt out of AI-based care without facing any discrimination or compromise in the quality of their treatment. 

4. Autonomy

AI should serve as a tool to support, not replace, human judgment in healthcare. Patient autonomy must always be respected and prioritized, especially when AI is involved in decision-making related to their health. Patients should have the right to make informed choices about their care, even when it conflicts with AI's judgment. Additionally, access to Protected Health Information (PHI) is a fundamental patient right, and providers must seek permission before using or sharing this information.

Ensure Data Privacy and Security

AI systems are like honey pots, drawing in cybercriminals. They are treasure troves of valuable data, making them prime targets for cyberattacks. The Health Insurance Portability and Accountability Act (HIPAA) enforces stringent data privacy and security regulations to mitigate these risks. However, with the increasing number of cyberattacks on healthcare organizations, it’s clear that existing measures need continuous strengthening. Healthcare providers must implement robust security protocols, including advanced encryption, strict access controls, and regular monitoring to safeguard data during collection, storage, or analysis.

Additionally, practices should conduct regular security audits and vulnerability assessments to identify potential weak points in their AI systems. Employees must also undergo continuous training on HIPAA compliance and develop an incident response plan to address potential breaches. 

Reach out to your insurance provider to understand the extent of your practice's AI coverage. Understanding your policy helps mitigate risks, manage potential liabilities tied to AI-assisted decisions, and ensure adequate protection in case of errors or disputes stemming from AI recommendations. 

Evaluate AI Algorithms

Implementing an AI system is just the beginning. AI tools must be continuously monitored, refined, and evaluated for accuracy, fairness, and real-world applicability to ensure their success. Here’s how healthcare providers can responsibly evaluate AI algorithms:

  • Measure Performance Metrics — Assess for accuracy, sensitivity, and specificity to ensure they meet clinical needs. Test in real-world scenarios and diverse patient populations to confirm consistent and reliable performance across varying environments.
  • Monitor and Refine — Update to remain effective and fair. Regularly monitor and refine to detect biases and discrepancies and ensure the system aligns with evolving clinical guidelines and patient needs.
  • Create Feedback Channels — Clinicians play a critical role in evaluating AI tools. Establish feedback mechanisms to gather insights on performance and identify areas for improvement.
  • Leverage Professional Expertise Medical societies provide vital frameworks and standards for evaluating AI medical intervention and ensure tools align with best practices and patient safety goals.

Maintain Oversight in AI-Assisted Decisions

AI technology has proven to be a powerful tool in healthcare, but it’s not error-proof. It is designed to augment, not replace, a physician’s expertise. While it can analyze large volumes of data with incredible speed and identify patterns, it’s not yet ready to replace human judgment, especially when lives are at stake. It lacks the nuanced understanding of the context that healthcare professionals bring to decision-making. Moreover, AI outcomes can be biased. That’s why human oversight is vital. Physicians must validate AI outputs without cognitive bias before acting on them, ensuring safe, ethical, and effective patient care.

Keep Pace with Evolving AI Knowledge

The effective use of AI requires the skills to evaluate, interpret, and collaborate with AI systems. While this might initially seem outside the traditional scope of clinical expertise, staying informed about AI tools is becoming imperative for modern medical practices.

AI augments decision-making. It provides insights and recommendations that complement physician expertise. Understanding how these algorithms work empowers physicians to critically assess their recommendations and ensure they align with clinical evidence and patient needs. Moreover, keeping pace with AI developments allows healthcare providers to contribute to refining these tools. 

Practice Caution 

One crucial factor when adopting new technologies like AI is to remain vigilant and always exercise caution. This is particularly important given the presence of many AI systems that have not undergone FDA review or institutional assessment. For instance, while AI technology can provide valuable insights, such as suggesting possible diagnoses or flagging abnormalities in imaging, the ultimate responsibility for decisions must always lie with the physician. This ensures that decisions are rooted in clinical judgment and adhere to established standards of care.

Monitor Developments in AI-Related Policies

AI is a rapidly advancing technology; the policies and regulations surrounding its application are still taking shape. In this dynamic landscape, healthcare practices must stay vigilant, actively monitoring new policies and guidelines to remain compliant. Falling behind on regulatory updates could lead to unintended consequences, including legal risks or ethical missteps.

The American Medical Association (AMA) offers specialized training for physicians to help them navigate AI ethics and legal considerations in healthcare. These resources are invaluable, offering insights into best practices and preparing providers to adapt their workflows to align with changing regulations.

AI holds immense potential to revolutionize healthcare, enhance diagnostic accuracy, streamline workflows, and improve patient outcomes. However, this transformative technology must be approached responsibly, upholding ethics and safety. After all, while AI brings innovation, the human touch ensures healthcare remains compassionate, effective, and trustworthy.

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